What does that have to do with women's health? It feels scary because, okay, again, politics again, in the 1990s, there was a big doping scandal where all these bodybuilders got testosterone in trouble and these body- Actually, I believe very strongly that when you give women information about how their bodies work, they make just excellent healthcare decisions for themselves. So in your 30s, if you have low libido, pain with sex, changes in your arousal or orgasm in your 30s, there is likely a biological basis and it likely has something to do with testosterone. I often start with estrogen and progesterone for many people because the hot flashes are so bad, the sleep is so bad. And as long as the total testosterone was not astronomically high, then you would qualify for a trial of testosterone therapy. So it's not as precise as we wish it were because no money goes into women's health and we don't have a product.
Studies conducted have found direct correlation between testosterone and dominance, especially among the most violent criminals in prison who had the highest testosterone. The first is the challenge hypothesis which states that testosterone would increase during puberty, thus facilitating reproductive and competitive behavior which would include aggression. There are two theories on the role of testosterone in aggression and competition. Studies have found that testosterone facilitates aggression by modulating vasopressin receptors in the hypothalamus.
(LH more often stimulates the production of estrogen and progesterone in ovaries.) LH then travels to your gonads and stimulates the production and release of testosterone. Your hypothalamus releases gonadotropin-releasing hormone (GnRH), which triggers your pituitary gland to release luteinizing hormone (LH). Your hypothalamus and pituitary gland control the amount of testosterone your gonads (testicles or ovaries) produce and release. Levels are usually highest in the morning and decline during the day.
Many people wonder whether it’s safe to take DHEA and testosterone together. As we age, or in cases of stress, illness, or hormonal imbalance, testosterone levels can dip. For some, the decline is steep and happens early on, especially if you are under chronic stress, not getting enough sleep, or have other underlying health conditions. To use a simple analogy, think of your hormones as the seed and DHEA as the water that makes it germinate. And, if your testosterone levels are lacking, how can DHEA help get things back on track?
Examples include genital virilisation such as midline fusion, phallic urethra, scrotal thinning and rugation, and phallic enlargement; although the role of testosterone is far smaller than that of dihydrotestosterone. The relative potency of these effects can depend on various factors and is a topic of ongoing research. Testosterone can be described as having anabolic and androgenic (virilising) effects, though these categorical descriptions are somewhat arbitrary, as there is a great deal of mutual overlap between them. In general, androgens such as testosterone promote protein synthesis and thus growth of tissues with androgen receptors.
The key is requesting a comprehensive panel that includes both adrenal and sex hormone markers, and understanding that timing matters enormously for hormone testing in premenopausal women. Post-menopausal women typically need adrenal restoration plus DHEA support to compensate for the loss of ovarian sex hormone precursor production. The body is supposed to compensate partly through adrenal production of sex hormone precursors. Oh, it has a lot to do with women's health because these bodybuilders got us in trouble and everyone was afraid that everyone was abusing testosterone. Nobody even considered estrogen and hormone therapy as part of maybe something that we should be talking about. If you're not on hormones, this is not whole body hormone therapy.

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